SLC19A2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC19A2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,298 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SLC19A2-associated GO terms across cancer lineages are Vitamin B6 transport, Pyridoxine transport, and Water-soluble vitamin biosynthetic process. Each is linked with SLC19A2 in more than 16 cancer types. Because this analysis shows association rather than direction, both SLC19A2-to-partner and partner-to-SLC19A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vitamin B6 transport grouped by SLC19A2-low versus SLC19A2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC19A2→partner) and Y-score (partner→SLC19A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BREASTVitamin B6 transport →+1.279+1.145<.001<.001317
BREASTPyridoxine transport →+1.279+1.145<.001<.001317
LIVERWater-soluble vitamin biosynthetic process →+0.186+1.274<.001.001313
LIVERFolic acid transport →+0.198+1.042.001<.001214
CNSVitamin biosynthetic process →+0.120+0.840<.001<.001312
LIVERPyrimidine-containing compound transmembrane transport →+0.246+1.387<.001<.001312
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,298 associations by consensus.

Vitamin B6 transport by SLC19A2 expression — BREAST

Box plot of Vitamin B6 transport in SLC19A2-low vs SLC19A2-high samples in BREAST.

Explore this box plot interactively →

Exploration