SLC19A1

Across TCGA patient cohorts, SLC19A1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,694 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SLC19A1-associated genes across cancer lineages are IQGAP1, SUV39H2, and PCLAF. Each is linked with SLC19A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC19A1-to-partner and partner-to-SLC19A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC19A1 versus IQGAP1 in OV, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC19A1→partner) and Y-score (partner→SLC19A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	IQGAP1 →	-0.743	-0.948	<.001	.002	3	3
GBM	SUV39H2 →	+0.558	+0.302	<.001	.001	3	3
UCEC	PCLAF →	+0.697	+0.429	<.001	<.001	3	3
GBM	ZNF273 →	+0.653	+0.322	<.001	<.001	3	3
LSCC	COPS3 →	+0.309	+0.191	.006	.001	3	2
CCRCC	CD163 →	+0.925	+0.492	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,694 associations by consensus.

SLC19A1 vs IQGAP1 — OV

Explore this scatter interactively →