SLC19A1

Across TCGA cell cohorts, SLC19A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,544 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible SLC19A1-associated GO terms across cancer lineages are Folic acid-containing compound metabolic process, XMP metabolic process, and XMP biosynthetic process. Each is linked with SLC19A1 in more than 16 cancer types. Because this analysis shows association rather than direction, both SLC19A1-to-partner and partner-to-SLC19A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Folic acid-containing compound metabolic process grouped by SLC19A1-low versus SLC19A1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC19A1→partner) and Y-score (partner→SLC19A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Folic acid-containing compound metabolic process →	+0.112	+1.183	<.001	<.001	3	17
PANCREAS	XMP metabolic process →	+0.199	+1.300	<.001	<.001	3	17
PANCREAS	XMP biosynthetic process →	+0.199	+1.300	<.001	<.001	3	17
PANCREAS	'de novo' XMP biosynthetic process →	+0.199	+1.300	<.001	<.001	3	17
LUNG_NSCLC_LUAD	Folic acid metabolic process →	+0.144	+0.974	<.001	<.001	3	16
BONE	IMP biosynthetic process →	+0.226	+1.560	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,544 associations by consensus.

Folic acid-containing compound metabolic process by SLC19A1 expression — URINARY_TRACT

Explore this box plot interactively →