SLC19A1

Across TCGA cell cohorts, SLC19A1 mutation is significantly associated with the RNA expression of many other genes, with 139 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC19A1-associated genes across cancer lineages are DAZ3, CTXN3, and SLC32A1. Each is linked with SLC19A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC19A1-to-partner and partner-to-SLC19A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DAZ3 grouped by SLC19A1-low versus SLC19A1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC19A1→partner) and Y-score (partner→SLC19A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	DAZ3 →	+0.484	+3.793	.008	.007	3	1
SKIN	CTXN3 →	+0.138	+3.920	<.001	.005	3	1
BLOOD_Leukemia	SLC32A1 →	+0.417	+2.901	<.001	.002	3	1
BLOOD_Leukemia	LGI1 →	+0.042	+3.316	<.001	.003	3	1
BLOOD_Leukemia	MTNR1B →	+0.060	+3.121	<.001	<.001	3	1
BLOOD_Leukemia	ABCG5 →	+0.043	+4.212	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 139 associations by consensus.

DAZ3 by SLC19A1 expression — SKIN

Explore this box plot interactively →