SLC18B1

Across TCGA patient cohorts, SLC18B1 mutation is significantly associated with the RNA expression of many other genes, with 1,036 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC18B1-associated genes across cancer lineages are NFYBP1, PRDX3P3, and RPL35AP31. Each is linked with SLC18B1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC18B1-to-partner and partner-to-SLC18B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NFYBP1 grouped by SLC18B1-low versus SLC18B1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC18B1→partner) and Y-score (partner→SLC18B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	NFYBP1 →	+0.077	+3.975	.004	.006	3	2
SKCM	PRDX3P3 →	+0.145	+5.682	<.001	<.001	3	2
CESC	RPL35AP31 →	+0.151	+4.269	.001	.003	3	2
LUAD	RNU4ATAC5P →	+0.279	+7.930	<.001	.008	3	2
COAD	BLOC1S2P1 →	+0.301	+4.080	<.001	.002	3	2
COAD	OSBPL9P5 →	+0.300	+5.734	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,036 associations by consensus.

NFYBP1 by SLC18B1 expression — CESC

Explore this box plot interactively →