SLC18B1

Across TCGA cell cohorts, SLC18B1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,957 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SLC18B1-associated GO terms across cancer lineages are Serotonin uptake, Spermidine transport, and Serotonin transport. Each is linked with SLC18B1 in more than 16 cancer types. Because this analysis shows association rather than direction, both SLC18B1-to-partner and partner-to-SLC18B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Serotonin uptake grouped by SLC18B1-low versus SLC18B1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC18B1→partner) and Y-score (partner→SLC18B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Serotonin uptake →	+1.599	+1.405	<.001	<.001	3	17
SKIN	Spermidine transport →	+1.423	+1.841	<.001	<.001	3	16
URINARY_TRACT	Serotonin transport →	+1.819	+1.454	<.001	<.001	3	14
SKIN	Spermine transport →	+0.209	+2.202	<.001	<.001	3	12
BONE	Regulation of thrombin-activated receptor signaling pathway →	-1.134	-1.248	<.001	<.001	3	10
BONE	Negative regulation of thrombin-activated receptor signaling pathway →	-1.134	-1.248	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,957 associations by consensus.

Serotonin uptake by SLC18B1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →