SLC18B1

Across TCGA cell cohorts, SLC18B1 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC18B1-associated genes across cancer lineages are CDY2A, IFNA4, and FAM240A. Each is linked with SLC18B1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC18B1-to-partner and partner-to-SLC18B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDY2A grouped by SLC18B1-low versus SLC18B1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC18B1→partner) and Y-score (partner→SLC18B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	CDY2A →	+0.009	+4.321	<.001	.009	3	1
CNS	IFNA4 →	+0.160	+4.321	<.001	.009	3	1
CNS	FAM240A →	+0.012	+4.169	.004	.008	3	1
LARGE_INTESTINE	PRSS54 →	+0.038	+3.345	<.001	.007	3	1
LARGE_INTESTINE	CNMD →	+0.030	+3.453	<.001	.009	3	1
LARGE_INTESTINE	UTF1 →	+0.018	+3.632	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

CDY2A by SLC18B1 expression — CNS

Explore this box plot interactively →