Across TCGA patient cohorts, SLC18A3 mutation is significantly associated with the RNA expression of many other genes, with 5,411 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC18A3-associated genes across cancer lineages are RNU1-35P, ENO2, and COX10. Each is linked with SLC18A3 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC18A3-to-partner and partner-to-SLC18A3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC18A3→partner) and Y-score (partner→SLC18A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU1-35P →	+0.227	+2.628	<.001	.002	3	4
COAD	ENO2 →	+0.952	+3.700	<.001	.001	3	4
UCEC	COX10 →	+0.410	+2.678	<.001	<.001	3	4
UCEC	SEH1L →	+0.478	+4.180	<.001	<.001	3	4
COAD	RPL17P50 →	+0.551	+2.846	<.001	.001	3	4
UCEC	NDUFA12 →	+0.270	+1.658	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,411 associations by consensus.

Exploration

SLC18A3 survival (RNA) · tumor vs normal (RNA) · all SLC18A3 data types