SLC18A3

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC18A3 mutation is significantly associated with the total protein of many other genes, with 50 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC18A3-associated genes across cancer lineages are FASN, PDCD4, and Smad4. Each is linked with SLC18A3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC18A3-to-partner and partner-to-SLC18A3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC18A3→partner) and Y-score (partner→SLC18A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADFASN →+0.384+2.230.010.00632
COADPDCD4 →-0.399-2.321.013.03332
COADSmad4 →+0.144+2.700.004.00532
COADSTAT5a →-0.488-1.691.018.04332
COADTuberin →-0.331-1.691.006.04332
COADASNS →+0.382+2.459.011.01832
Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

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