SLC18A2

Across TCGA patient cohorts, SLC18A2 protein abundance is significantly associated with the RNA expression of many other genes, with 686 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SLC18A2-associated genes across cancer lineages are PFDN4, USP14, and RNMT. Each is linked with SLC18A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC18A2-to-partner and partner-to-SLC18A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC18A2 versus PFDN4 in LUAD, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC18A2→partner) and Y-score (partner→SLC18A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PFDN4 →	-0.752	-0.920	<.001	.002	3	1
LUAD	USP14 →	-0.831	-1.174	<.001	<.001	3	1
LUAD	RNMT →	-0.626	-1.077	.001	.004	3	1
LUAD	NKAP →	-0.453	-0.956	.003	.007	3	1
LUAD	EEA1 →	-0.351	-0.700	.002	.005	3	1
LUAD	GLA →	-0.572	-1.123	.005	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 686 associations by consensus.

SLC18A2 vs PFDN4 — LUAD

Explore this scatter interactively →