SLC18A2

Across TCGA patient cohorts, SLC18A2 mutation is significantly associated with the total protein of many other genes, with 40 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC18A2-associated genes across cancer lineages are eIF4E, PCNA, and eEF2. Each is linked with SLC18A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC18A2-to-partner and partner-to-SLC18A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4E grouped by SLC18A2-low versus SLC18A2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC18A2→partner) and Y-score (partner→SLC18A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.230	+2.169	.003	.003	3	3
UCEC	PCNA →	+0.166	+1.700	.040	.042	3	3
UCEC	eEF2 →	+0.370	+1.765	.005	.014	3	2
UCEC	ETS-1 →	+0.237	+2.321	.047	.034	3	2
UCEC	GAPDH →	+0.545	+3.321	.006	.009	3	2
UCEC	PEA-15_pS116 →	+0.272	+2.000	.039	.030	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

eIF4E by SLC18A2 expression — UCEC

Explore this box plot interactively →