SLC18A2

Across TCGA cell cohorts, SLC18A2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,766 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC18A2-associated GO terms across cancer lineages are Proximal tubule development, Positive regulation of receptor localization to synapse, and Serotonin biosynthetic process. Each is linked with SLC18A2 in more than 5 cancer types. Because this analysis shows association rather than direction, both SLC18A2-to-partner and partner-to-SLC18A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proximal tubule development grouped by SLC18A2-low versus SLC18A2-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC18A2→partner) and Y-score (partner→SLC18A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Proximal tubule development →	-0.164	-0.491	.003	.006	3	6
LARGE_INTESTINE	Positive regulation of receptor localization to synapse →	-0.114	-0.310	.001	.006	3	5
LUNG_SCLC	Serotonin biosynthetic process →	+1.046	+1.566	<.001	.001	3	5
BLOOD_Leukemia	Negative regulation of dendrite development →	-0.116	-1.766	<.001	<.001	3	5
LARGE_INTESTINE	Lateral mesoderm development →	-0.144	-0.484	.001	.002	3	4
LUNG_NSCLC_LUAD	Modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration →	-0.085	-0.143	.004	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,766 associations by consensus.

Proximal tubule development by SLC18A2 expression — KIDNEY

Explore this box plot interactively →