SLC18A1

Across TCGA patient cohorts, SLC18A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,985 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible SLC18A1-associated GO terms across cancer lineages are Regulation of cell shape, B cell activation involved in immune response, and Obsolete regulation of transcription from RNA polymerase II promoter in response to stress. Each is linked with SLC18A1 in more than 17 cancer types. Because this analysis shows association rather than direction, both SLC18A1-to-partner and partner-to-SLC18A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cell shape grouped by SLC18A1-low versus SLC18A1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC18A1→partner) and Y-score (partner→SLC18A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of cell shape →	+0.072	+0.448	<.001	<.001	3	18
STAD	B cell activation involved in immune response →	+0.052	+0.312	<.001	<.001	3	18
STAD	Obsolete regulation of transcription from RNA polymerase II promoter in response to stress →	+0.058	+0.344	<.001	<.001	3	18
TGCT	Lymphocyte homeostasis →	+0.042	+0.666	<.001	<.001	3	17
STAD	Positive regulation of protein-containing complex assembly →	+0.057	+0.314	<.001	<.001	3	17
ESCA	Reactive oxygen species metabolic process →	+0.059	+1.086	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,985 associations by consensus.

Regulation of cell shape by SLC18A1 expression — STAD

Explore this box plot interactively →