SLC18A1

Across TCGA patient cohorts, SLC18A1 protein abundance is significantly associated with the RNA expression of many other genes, with 564 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SLC18A1-associated genes across cancer lineages are SEZ6L, CHGA, and SLC8A3. Each is linked with SLC18A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC18A1-to-partner and partner-to-SLC18A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC18A1 versus SEZ6L in GBM, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC18A1→partner) and Y-score (partner→SLC18A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SEZ6L →	+2.086	+0.541	.003	.009	3	1
GBM	CHGA →	+1.910	+0.642	<.001	.001	3	1
GBM	SLC8A3 →	+1.563	+0.796	<.001	<.001	3	1
GBM	HRH3 →	+0.650	+0.552	.004	.007	3	1
GBM	FGF9 →	+0.705	+0.821	.003	.002	3	1
GBM	PARP4 →	-0.362	-0.586	.003	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 564 associations by consensus.

SLC18A1 vs SEZ6L — GBM

Explore this scatter interactively →