SLC18A1

Across TCGA cell cohorts, SLC18A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,832 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SLC18A1-associated GO terms across cancer lineages are Peristalsis, Negative regulation of retinoic acid receptor signaling pathway, and Negative regulation of ruffle assembly. Each is linked with SLC18A1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SLC18A1-to-partner and partner-to-SLC18A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peristalsis grouped by SLC18A1-low versus SLC18A1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC18A1→partner) and Y-score (partner→SLC18A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Peristalsis →	+1.735	+1.749	<.001	<.001	3	4
LUNG_SCLC	Negative regulation of retinoic acid receptor signaling pathway →	+0.177	+1.528	.001	.005	2	5
SOFT_TISSUE	Negative regulation of ruffle assembly →	-0.144	-0.574	.004	.005	3	4
SOFT_TISSUE	Regulation of viral budding via host ESCRT complex →	+0.070	+0.574	.007	.002	3	4
SOFT_TISSUE	Positive regulation of viral budding via host ESCRT complex →	+0.070	+0.574	.007	.002	3	4
SOFT_TISSUE	Positive regulation of natural killer cell activation →	-0.170	-0.811	.002	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,832 associations by consensus.

Peristalsis by SLC18A1 expression — SKIN

Explore this box plot interactively →