SLC18A1

Across TCGA cell cohorts, SLC18A1 mutation is significantly associated with the mutation status of many other genes, with 4,409 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC18A1-associated genes across cancer lineages are WDR19, B3GALT1, and OR5AS1. Each is linked with SLC18A1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC18A1-to-partner and partner-to-SLC18A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, WDR19 grouped by SLC18A1-low versus SLC18A1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC18A1→partner) and Y-score (partner→SLC18A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	WDR19 →	+4.014	+4.969	.008	.008	1	4
BLOOD_Lymphoma	B3GALT1 →	+5.014	+5.584	.003	.003	1	4
BLOOD_Lymphoma	OR5AS1 →	+6.014	+6.014	.001	.001	1	4
BLOOD_Lymphoma	MAN1A2 →	+4.429	+5.247	.005	.005	1	4
BLOOD_Lymphoma	GRM3 →	+4.429	+5.247	.005	.005	1	4
LARGE_INTESTINE	THADA →	+2.777	+3.767	<.001	<.001	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,409 associations by consensus.

WDR19 by SLC18A1 expression — BLOOD_Lymphoma

Explore this box plot interactively →