SLC17A8

Across TCGA patient cohorts, SLC17A8 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,095 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SLC17A8-associated GO terms across cancer lineages are Multivesicular body organization, ERAD pathway, and Late endosome to vacuole transport. Each is linked with SLC17A8 in more than 18 cancer types. Because this analysis shows association rather than direction, both SLC17A8-to-partner and partner-to-SLC17A8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Multivesicular body organization grouped by SLC17A8-low versus SLC17A8-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC17A8→partner) and Y-score (partner→SLC17A8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Multivesicular body organization →	+0.109	+0.220	<.001	<.001	2	19
ESCA	ERAD pathway →	+0.084	+0.188	<.001	<.001	3	17
STAD	Late endosome to vacuole transport →	+0.107	+0.291	<.001	<.001	2	17
STAD	Positive regulation of mRNA metabolic process →	+0.064	+0.235	<.001	<.001	3	16
STAD	Regulation of RNA splicing →	+0.082	+0.267	<.001	<.001	3	16
STAD	Regulation of mRNA splicing, via spliceosome →	+0.082	+0.251	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,095 associations by consensus.

Multivesicular body organization by SLC17A8 expression — STAD

Explore this box plot interactively →