SLC17A8

Across TCGA patient cohorts, SLC17A8 mutation is significantly associated with the RNA expression of many other genes, with 3,587 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC17A8-associated genes across cancer lineages are H3P29, RNU6ATAC28P, and TCF3. Each is linked with SLC17A8 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC17A8-to-partner and partner-to-SLC17A8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, H3P29 grouped by SLC17A8-low versus SLC17A8-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC17A8→partner) and Y-score (partner→SLC17A8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	H3P29 →	+0.104	+1.931	<.001	.007	3	3
LUSC	RNU6ATAC28P →	+0.106	+2.359	<.001	.008	3	3
UCEC	TCF3 →	+0.657	+3.847	<.001	<.001	3	3
COAD	RPL22P6 →	+0.090	+5.136	<.001	.002	3	3
STAD	RNU6-709P →	+0.396	+3.646	.001	.009	3	3
UCEC	MAP3K8 →	-0.538	-2.116	.004	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,587 associations by consensus.

H3P29 by SLC17A8 expression — LUSC

Explore this box plot interactively →