SLC17A8

Across TCGA cell cohorts, SLC17A8 RNA expression is significantly associated with the go_rna of many other GO terms, with 880 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SLC17A8-associated GO terms across cancer lineages are Cytoplasmic translation, Negative regulation of syncytium formation by plasma membrane fusion, and Vesicle coating. Each is linked with SLC17A8 in more than 6 cancer types. Because this analysis shows association rather than direction, both SLC17A8-to-partner and partner-to-SLC17A8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translation grouped by SLC17A8-low versus SLC17A8-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC17A8→partner) and Y-score (partner→SLC17A8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Cytoplasmic translation →	+0.047	+0.040	.003	.005	3	6
OVARY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.084	+0.030	.009	.008	2	7
LUNG_SCLC	Vesicle coating →	+0.094	+0.448	<.001	.002	3	6
LUNG_NSCLC_LUSC	Positive regulation of post-translational protein modification →	+0.060	+0.052	<.001	.001	3	5
LUNG_NSCLC_LUSC	Purine nucleoside triphosphate biosynthetic process →	+0.121	+0.060	<.001	<.001	3	5
LUNG_NSCLC_LUSC	Purine ribonucleoside triphosphate biosynthetic process →	+0.121	+0.060	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 880 associations by consensus.

Cytoplasmic translation by SLC17A8 expression — LARGE_INTESTINE

Explore this box plot interactively →