SLC17A7

Across TCGA patient cohorts, SLC17A7 mutation is significantly associated with the RNA expression of many other genes, with 2,040 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC17A7-associated genes across cancer lineages are TMEM269, COX15, and CPSF7. Each is linked with SLC17A7 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC17A7-to-partner and partner-to-SLC17A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TMEM269 grouped by SLC17A7-low versus SLC17A7-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC17A7→partner) and Y-score (partner→SLC17A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	TMEM269 →	+0.242	+2.525	<.001	.009	3	3
SKCM	COX15 →	+0.486	+3.341	.005	.005	3	2
SKCM	CPSF7 →	+0.443	+2.591	.004	.006	3	2
SKCM	PRSS53 →	+0.433	+2.604	.001	.006	3	2
UCEC	NOCT →	+0.587	+1.934	<.001	.002	3	2
UCEC	GPATCH11 →	+0.393	+1.958	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,040 associations by consensus.

TMEM269 by SLC17A7 expression — SKCM

Explore this box plot interactively →