SLC17A5

Across TCGA pan-cancer cohorts, SLC17A5 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SLC17A5 data layer compared with 23 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher SLC17A5 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SLC17A5 expression acts as an unfavorable survival marker, although some lineages such as COAD and LSCC show a favorable association.

COAD, LUAD, and CCRCC are the cancer types where SLC17A5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	1.000	0.926	.021	36	view →
LUAD	DFS	Tertile	All	0.799	0.999	.005	7	view →
CCRCC	DFS	Tertile	All	0.716	0.888	.024	3	view →
LSCC	OS	Tertile	III,IV	1.000	0.553	.026	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SLC17A5–COAD (DFS)

Open the COAD breakdown →