SLC17A5

Across TCGA patient cohorts, SLC17A5 mutation is significantly associated with the RNA expression of many other genes, with 1,735 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC17A5-associated genes across cancer lineages are RNA5SP436, SPATA31E3P, and LINC02103. Each is linked with SLC17A5 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC17A5-to-partner and partner-to-SLC17A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP436 grouped by SLC17A5-low versus SLC17A5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC17A5→partner) and Y-score (partner→SLC17A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP436 →	+0.407	+3.559	<.001	<.001	3	3
BRCA	SPATA31E3P →	+0.009	+4.721	<.001	.007	3	2
BRCA	LINC02103 →	+0.290	+4.721	<.001	.007	3	2
LUAD	OR2AP1 →	+0.091	+6.584	<.001	.001	3	2
LGG	RNU6-480P →	+0.313	+7.977	<.001	.007	3	2
BLCA	RAD52P1 →	+0.052	+7.040	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,735 associations by consensus.

RNA5SP436 by SLC17A5 expression — UCEC

Explore this box plot interactively →