SLC17A4

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC17A4 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,151 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC17A4-associated GO terms across cancer lineages are Renal D-glucose absorption, Primary amino compound biosynthetic process, and Brush border assembly. Each is linked with SLC17A4 in more than 5 cancer types. Because this analysis shows association rather than direction, both SLC17A4-to-partner and partner-to-SLC17A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Renal D-glucose absorption grouped by SLC17A4-low versus SLC17A4-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC17A4→partner) and Y-score (partner→SLC17A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINERenal D-glucose absorption →+1.157+0.492<.001<.00136
LUNG_SCLCPrimary amino compound biosynthetic process →+1.655+0.518<.001<.00135
KIDNEYBrush border assembly →+0.889+0.377.001.00335
LARGE_INTESTINESerotonin biosynthetic process →+1.846+0.663<.001<.00135
LARGE_INTESTINEIndole-containing compound biosynthetic process →+1.985+0.575<.001<.00135
KIDNEYPositive regulation of collagen metabolic process →-0.196-0.399<.001.00235
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,151 associations by consensus.

Renal D-glucose absorption by SLC17A4 expression — LARGE_INTESTINE

Box plot of Renal D-glucose absorption in SLC17A4-low vs SLC17A4-high samples in LARGE_INTESTINE.

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Exploration