SLC17A4

Across TCGA cell cohorts, SLC17A4 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC17A4-associated genes across cancer lineages are OR2C3 and SLC15A5. Each is linked with SLC17A4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC17A4-to-partner and partner-to-SLC17A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2C3 grouped by SLC17A4-low versus SLC17A4-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC17A4→partner) and Y-score (partner→SLC17A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR2C3 →	+1.172	+4.887	<.001	.009	3	1
LARGE_INTESTINE	SLC15A5 →	+0.017	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR2C3 by SLC17A4 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →