SLC17A3

Across TCGA patient cohorts, SLC17A3 protein abundance is significantly associated with the RNA expression of many other genes, with 558 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SLC17A3-associated genes across cancer lineages are GGTLC2, HMOX1, and PFDN4. Each is linked with SLC17A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC17A3-to-partner and partner-to-SLC17A3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC17A3 versus GGTLC2 in CCRCC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC17A3→partner) and Y-score (partner→SLC17A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	GGTLC2 →	+0.190	+0.406	.002	.007	3	1
CCRCC	HMOX1 →	+0.606	+0.518	<.001	<.001	3	1
CCRCC	PFDN4 →	-0.243	-0.467	.005	.001	3	1
CCRCC	RIOK3 →	+0.290	+0.493	.004	.003	3	1
CCRCC	PLP2 →	-0.649	-0.465	.005	.006	3	1
CCRCC	AP3B2 →	-0.402	-0.453	.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 558 associations by consensus.

SLC17A3 vs GGTLC2 — CCRCC

Explore this scatter interactively →