SLC17A3

Across TCGA patient cohorts, SLC17A3 mutation is significantly associated with the RNA expression of many other genes, with 4,047 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC17A3-associated genes across cancer lineages are LINC02672, RCCD1, and EME1. Each is linked with SLC17A3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC17A3-to-partner and partner-to-SLC17A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02672 grouped by SLC17A3-low versus SLC17A3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC17A3→partner) and Y-score (partner→SLC17A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC02672 →	+1.261	+1.716	<.001	.002	3	3
LUAD	RCCD1 →	+0.528	+3.204	.003	.009	3	3
UCEC	EME1 →	+0.393	+1.332	.008	.008	3	3
UCEC	GPER1 →	-0.659	-2.321	<.001	.001	3	3
UCEC	ZMYND19 →	+0.407	+2.502	<.001	.001	3	3
UCEC	COX11 →	+0.338	+1.773	.006	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,047 associations by consensus.

LINC02672 by SLC17A3 expression — UCEC

Explore this box plot interactively →