SLC17A3

Across TCGA cell cohorts, SLC17A3 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SLC17A3-associated genes across cancer lineages are TINAG, GPR152, and C4orf50. Each is linked with SLC17A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC17A3-to-partner and partner-to-SLC17A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TINAG grouped by SLC17A3-low versus SLC17A3-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC17A3→partner) and Y-score (partner→SLC17A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	TINAG →	+0.216	+3.678	<.001	.009	3	1
SKIN	GPR152 →	+0.055	+4.347	<.001	.001	3	1
SKIN	C4orf50 →	+0.022	+3.684	<.001	.006	3	1
BLOOD_Lymphoma	KIF2B →	+0.006	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	OR10P1 →	+0.649	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	OR4F6 →	+0.019	+5.209	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

TINAG by SLC17A3 expression — SKIN

Explore this box plot interactively →