SLC17A2

Across TCGA patient cohorts, SLC17A2 mutation is significantly associated with the RNA expression of many other genes, with 2,200 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC17A2-associated genes across cancer lineages are ZWINT, ELK1, and NDUFB10P1. Each is linked with SLC17A2 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC17A2-to-partner and partner-to-SLC17A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZWINT grouped by SLC17A2-low versus SLC17A2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC17A2→partner) and Y-score (partner→SLC17A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZWINT →	+0.679	+2.666	.004	.005	3	3
UCEC	ELK1 →	+0.430	+2.436	.006	.002	3	3
UCEC	NDUFB10P1 →	+0.160	+1.951	.001	.002	3	3
SKCM	CFI →	-0.990	-1.861	.004	<.001	3	3
SKCM	GCAT →	+0.512	+2.079	.002	<.001	3	3
SKCM	UBE2M →	+0.310	+2.125	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,200 associations by consensus.

ZWINT by SLC17A2 expression — UCEC

Explore this box plot interactively →