SLC17A2

Across TCGA patient cohorts, SLC17A2 mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC17A2-associated genes across cancer lineages are HER2_pY1248, 14-3-3_beta, and Heregulin. Each is linked with SLC17A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC17A2-to-partner and partner-to-SLC17A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HER2_pY1248 grouped by SLC17A2-low versus SLC17A2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC17A2→partner) and Y-score (partner→SLC17A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	HER2_pY1248 →	-0.105	-1.999	.040	.002	3	3
UCEC	14-3-3_beta →	-0.121	-2.432	.005	.018	3	2
UCEC	Heregulin →	-0.169	-2.115	.001	.019	3	2
UCEC	Rab11 →	-0.145	-3.302	.022	.010	3	2
UCEC	Caspase-7-cleavedD198 →	+0.603	+2.115	.020	.019	3	2
UCEC	CD31 →	-0.127	-2.115	.048	.019	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

HER2_pY1248 by SLC17A2 expression — SKCM

Explore this box plot interactively →