SLC17A1

Across TCGA patient cohorts, SLC17A1 mutation is significantly associated with the total protein of many other genes, with 51 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC17A1-associated genes across cancer lineages are PCNA, 4E-BP1, and eEF2. Each is linked with SLC17A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC17A1-to-partner and partner-to-SLC17A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCNA grouped by SLC17A1-low versus SLC17A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC17A1→partner) and Y-score (partner→SLC17A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.218	+2.222	.005	.010	3	3
UCEC	4E-BP1 →	+0.240	+2.730	.013	.003	3	3
UCEC	eEF2 →	+0.336	+1.925	.009	.005	3	2
UCEC	eIF4G →	+0.259	+2.222	.020	.010	3	2
UCEC	GAPDH →	+0.475	+1.584	.014	.019	3	2
UCEC	JNK_pT183_Y185 →	-0.201	-3.087	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

PCNA by SLC17A1 expression — UCEC

Explore this box plot interactively →