SLC17A1

Across TCGA cell cohorts, SLC17A1 mutation is significantly associated with the RNA expression of many other genes, with 333 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC17A1-associated genes across cancer lineages are OR5A1, USP17L17, and CBY1. Each is linked with SLC17A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC17A1-to-partner and partner-to-SLC17A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR5A1 grouped by SLC17A1-low versus SLC17A1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC17A1→partner) and Y-score (partner→SLC17A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR5A1 →	+0.015	+5.209	.008	.005	3	1
BLOOD_Lymphoma	USP17L17 →	+0.023	+6.247	<.001	<.001	3	1
LARGE_INTESTINE	CBY1 →	+0.708	+3.299	<.001	.004	3	1
LARGE_INTESTINE	SH3GL2 →	+1.250	+3.474	<.001	.003	3	1
LARGE_INTESTINE	TRIM37 →	+0.761	+3.212	<.001	.006	3	1
LARGE_INTESTINE	PMP22 →	+1.415	+3.212	.006	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 333 associations by consensus.

OR5A1 by SLC17A1 expression — BLOOD_Lymphoma

Explore this box plot interactively →