SLC16A8

Across TCGA pan-cancer cohorts, SLC16A8 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated SLC16A8 data layer compared with 24 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher SLC16A8 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated SLC16A8 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LSCC show a favorable association.

UCEC, CCRCC, and PDAC are the cancer types where SLC16A8 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	II,III,IV	1.000	0.331	.022	16	view →
CCRCC	DFS	Tertile	All	0.620	0.946	.008	8	view →
PDAC	DFS	Median	IV	0.255	0.741	.038	3	view →
LSCC	OS	Median	All	1.000	0.526	.040	2	view →
GBM	DFS	Median	All	0.278	0.463	.024	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

SLC16A8–UCEC (OS)

Open the UCEC breakdown →