SLC16A7

Across TCGA patient cohorts, SLC16A7 mutation is significantly associated with the RNA expression of many other genes, with 1,985 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC16A7-associated genes across cancer lineages are PPP1R11P2, CCM2L, and MX2. Each is linked with SLC16A7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC16A7-to-partner and partner-to-SLC16A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PPP1R11P2 grouped by SLC16A7-low versus SLC16A7-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A7→partner) and Y-score (partner→SLC16A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	PPP1R11P2 →	+0.179	+4.204	.003	.004	3	2
UCEC	CCM2L →	-0.344	-1.951	.008	.009	3	2
UCEC	MX2 →	-0.768	-3.989	<.001	<.001	3	2
UCEC	CDCA2 →	+0.781	+2.321	<.001	<.001	3	2
UCEC	NCR1 →	+0.196	+2.039	.006	.001	3	2
UCEC	ADAMTSL2 →	-0.748	-2.989	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,985 associations by consensus.

PPP1R11P2 by SLC16A7 expression — LUSC

Explore this box plot interactively →