SLC16A7

Across TCGA patient cohorts, SLC16A7 mutation is significantly associated with the total protein of many other genes, with 47 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC16A7-associated genes across cancer lineages are PDCD4, Caspase-7-cleavedD198, and 14-3-3_beta. Each is linked with SLC16A7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC16A7-to-partner and partner-to-SLC16A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDCD4 grouped by SLC16A7-low versus SLC16A7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A7→partner) and Y-score (partner→SLC16A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDCD4 →	-0.536	-2.058	<.001	<.001	3	2
UCEC	Caspase-7-cleavedD198 →	+0.563	+1.785	.002	.007	3	2
UCEC	14-3-3_beta →	-0.076	-1.780	.018	.024	3	1
UCEC	eEF2 →	+0.327	+2.222	.004	.009	3	1
UCEC	EGFR_pY1068 →	-0.203	-1.584	.011	.032	3	1
UCEC	eIF4E →	+0.165	+3.472	.014	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 47 associations by consensus.

PDCD4 by SLC16A7 expression — UCEC

Explore this box plot interactively →