SLC16A6

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC16A6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,305 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SLC16A6-associated GO terms across cancer lineages are Regulation of heart rate by cardiac conduction, Positive regulation of sodium ion transmembrane transport, and Cell junction assembly. Each is linked with SLC16A6 in more than 8 cancer types. Because this analysis shows association rather than direction, both SLC16A6-to-partner and partner-to-SLC16A6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of heart rate by cardiac conduction grouped by SLC16A6-low versus SLC16A6-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A6→partner) and Y-score (partner→SLC16A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UPPER_AERODIGESTIVE_TRACTRegulation of heart rate by cardiac conduction →-0.115-0.320.002.00239
SKINPositive regulation of sodium ion transmembrane transport →-0.168-2.927.002<.00137
UPPER_AERODIGESTIVE_TRACTCell junction assembly →-0.063-0.472.008.00536
BREASTSkeletal muscle tissue regeneration →-0.143-1.856.001<.00136
BREASTmiRNA transport →+0.093+1.352<.001<.00136
SKINEstablishment or maintenance of transmembrane electrochemical gradient →-0.212-3.835<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,305 associations by consensus.

Regulation of heart rate by cardiac conduction by SLC16A6 expression — UPPER_AERODIGESTIVE_TRACT

Box plot of Regulation of heart rate by cardiac conduction in SLC16A6-low vs SLC16A6-high samples in UPPER_AERODIGESTIVE_TRACT.

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Exploration