SLC16A6

Across TCGA cell cohorts, SLC16A6 mutation is significantly associated with the RNA expression of many other genes, with 503 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC16A6-associated genes across cancer lineages are CCDC134, PICK1, and CBY1. Each is linked with SLC16A6 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC16A6-to-partner and partner-to-SLC16A6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC134 grouped by SLC16A6-low versus SLC16A6-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A6→partner) and Y-score (partner→SLC16A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CCDC134 →	+0.776	+3.502	.001	.001	3	1
LARGE_INTESTINE	PICK1 →	+0.685	+3.169	.002	.009	3	1
LARGE_INTESTINE	CBY1 →	+0.725	+3.588	<.001	<.001	3	1
LARGE_INTESTINE	SLC25A17 →	+0.601	+3.502	.002	.001	3	1
LARGE_INTESTINE	USP14 →	+0.766	+3.588	<.001	<.001	3	1
LARGE_INTESTINE	SH3GL2 →	+1.289	+3.667	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 503 associations by consensus.

CCDC134 by SLC16A6 expression — LARGE_INTESTINE

Explore this box plot interactively →