SLC16A4

Across TCGA pan-cancer cohorts, SLC16A4 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SLC16A4 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher SLC16A4 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC16A4 expression acts as an unfavorable survival marker.

LSCC, LUAD, and CCRCC are the cancer types where SLC16A4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Quartile	II,III,IV	0.383	1.000	.002	47	view →
LUAD	DFS	Median	II,III,IV	0.170	0.601	.002	5	view →
CCRCC	DFS	Quartile	III,IV	0.233	0.887	.017	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

SLC16A4–LSCC (DFS)

Open the LSCC breakdown →