SLC16A4

Across TCGA cell cohorts, SLC16A4 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC16A4-associated genes across cancer lineages are MSGN1, SPINK9, and SPRR2F. Each is linked with SLC16A4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC16A4-to-partner and partner-to-SLC16A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MSGN1 grouped by SLC16A4-low versus SLC16A4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A4→partner) and Y-score (partner→SLC16A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MSGN1 →	+0.082	+3.345	<.001	.007	3	1
LARGE_INTESTINE	SPINK9 →	+0.285	+4.115	<.001	.001	3	1
LARGE_INTESTINE	SPRR2F →	+0.420	+3.766	.009	.004	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

MSGN1 by SLC16A4 expression — LARGE_INTESTINE

Explore this box plot interactively →