SLC16A3

Across TCGA patient cohorts, SLC16A3 mutation is significantly associated with the RNA expression of many other genes, with 324 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC16A3-associated genes across cancer lineages are MIR301B, MIR6876, and SNORD31B. Each is linked with SLC16A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC16A3-to-partner and partner-to-SLC16A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR301B grouped by SLC16A3-low versus SLC16A3-high in LGG.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A3→partner) and Y-score (partner→SLC16A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	MIR301B →	+0.568	+5.039	<.001	.009	3	2
UCEC	MIR6876 →	+0.561	+2.640	<.001	.003	3	2
LUAD	SNORD31B →	+0.754	+5.712	<.001	.003	3	2
LUAD	MIR4716 →	+0.603	+5.798	<.001	.003	3	2
CESC	TRAJ51 →	+0.321	+6.174	<.001	<.001	3	2
CESC	OR4A14P →	+0.021	+4.342	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 324 associations by consensus.

MIR301B by SLC16A3 expression — LGG

Explore this box plot interactively →