SLC16A3

Across TCGA cell cohorts, SLC16A3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,586 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC16A3-associated GO terms across cancer lineages are Lactate transport, Lactate transmembrane transport, and Plasma membrane lactate transport. Each is linked with SLC16A3 in more than 13 cancer types. Because this analysis shows association rather than direction, both SLC16A3-to-partner and partner-to-SLC16A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lactate transport grouped by SLC16A3-low versus SLC16A3-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A3→partner) and Y-score (partner→SLC16A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Lactate transport →	+0.715	+3.393	<.001	<.001	3	14
BREAST	Lactate transmembrane transport →	+0.715	+3.393	<.001	<.001	3	14
BREAST	Plasma membrane lactate transport →	+0.532	+2.522	<.001	<.001	3	14
BLOOD_Lymphoma	Urokinase plasminogen activator signaling pathway →	+1.253	+2.530	<.001	<.001	3	14
BONE	Regulation of cell-substrate adhesion →	+0.131	+2.927	<.001	<.001	3	14
BONE	Actin filament organization →	+0.141	+3.185	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,586 associations by consensus.

Lactate transport by SLC16A3 expression — BREAST

Explore this box plot interactively →