SLC16A2

Across TCGA cell cohorts, SLC16A2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,040 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC16A2-associated GO terms across cancer lineages are Negative regulation of organelle assembly, Regulation of hippo signaling, and Negative regulation of endodermal cell differentiation. Each is linked with SLC16A2 in more than 10 cancer types. Because this analysis shows association rather than direction, both SLC16A2-to-partner and partner-to-SLC16A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of organelle assembly grouped by SLC16A2-low versus SLC16A2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A2→partner) and Y-score (partner→SLC16A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Negative regulation of organelle assembly →	+0.079	+1.758	.005	.005	3	11
LIVER	Regulation of hippo signaling →	+0.096	+2.697	.003	.007	3	11
LUNG_NSCLC_LUSC	Negative regulation of endodermal cell differentiation →	+1.730	+2.434	<.001	.001	3	10
LUNG_NSCLC_LUSC	Negative regulation of protein modification by small protein conjugation or removal →	+0.094	+2.471	.004	<.001	2	11
LUNG_NSCLC_LUSC	Positive regulation of focal adhesion assembly →	+0.160	+2.277	.001	<.001	3	9
LIVER	Response to oscillatory fluid shear stress →	+0.140	+2.905	.006	.008	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,040 associations by consensus.

Negative regulation of organelle assembly by SLC16A2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →