SLC16A14

Across TCGA patient cohorts, SLC16A14 mutation is significantly associated with the total protein of many other genes, with 40 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC16A14-associated genes across cancer lineages are Notch1, PCNA, and STAT3_pY705. Each is linked with SLC16A14 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC16A14-to-partner and partner-to-SLC16A14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Notch1 grouped by SLC16A14-low versus SLC16A14-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A14→partner) and Y-score (partner→SLC16A14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.115	+1.820	.009	.014	3	2
UCEC	PCNA →	+0.241	+2.115	<.001	<.001	3	2
UCEC	STAT3_pY705 →	-0.265	-1.280	.001	.049	3	2
UCEC	VHL →	-0.568	-1.362	.007	.034	3	2
UCEC	EGFR_pY1068 →	-0.221	-2.115	.005	<.001	3	1
UCEC	eIF4E →	+0.166	+1.836	.012	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

Notch1 by SLC16A14 expression — UCEC

Explore this box plot interactively →