SLC16A14

Across TCGA cell cohorts, SLC16A14 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,859 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SLC16A14-associated GO terms across cancer lineages are Proteasomal ubiquitin-independent protein catabolic process, Negative regulation of mRNA metabolic process, and Detection of external biotic stimulus. Each is linked with SLC16A14 in more than 5 cancer types. Because this analysis shows association rather than direction, both SLC16A14-to-partner and partner-to-SLC16A14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proteasomal ubiquitin-independent protein catabolic process grouped by SLC16A14-low versus SLC16A14-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A14→partner) and Y-score (partner→SLC16A14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Proteasomal ubiquitin-independent protein catabolic process →	+0.098	+2.073	.001	.001	3	6
UPPER_AERODIGESTIVE_TRACT	Negative regulation of mRNA metabolic process →	+0.053	+1.011	<.001	.005	3	6
LUNG_SCLC	Detection of external biotic stimulus →	-0.173	-1.043	<.001	.003	3	6
BREAST	L-glutamine catabolic process →	-0.192	-1.413	.002	.003	3	6
UPPER_AERODIGESTIVE_TRACT	Response to lithium ion →	+0.129	+1.046	<.001	<.001	3	5
LUNG_SCLC	Spliceosomal complex assembly →	+0.087	+1.286	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,859 associations by consensus.

Proteasomal ubiquitin-independent protein catabolic process by SLC16A14 expression — LUNG_NSCLC_LUSC

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