SLC16A14

Across TCGA cell cohorts, SLC16A14 mutation is significantly associated with the RNA expression of many other genes, with 98 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC16A14-associated genes across cancer lineages are OR1L6, C2orf80, and USP17L22. Each is linked with SLC16A14 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC16A14-to-partner and partner-to-SLC16A14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1L6 grouped by SLC16A14-low versus SLC16A14-high in BONE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A14→partner) and Y-score (partner→SLC16A14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	OR1L6 →	+0.020	+5.169	<.001	.004	3	1
BONE	C2orf80 →	+0.126	+5.169	<.001	.004	3	1
BLOOD_Lymphoma	USP17L22 →	+0.019	+4.643	<.001	.005	3	1
LARGE_INTESTINE	SIRPB1 →	+0.462	+3.451	.005	.002	3	1
LARGE_INTESTINE	CST3 →	-1.012	-3.278	.002	.006	3	1
LARGE_INTESTINE	ZNF330 →	+0.483	+3.067	.006	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 98 associations by consensus.

OR1L6 by SLC16A14 expression — BONE

Explore this box plot interactively →