SLC16A13

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC16A13 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SLC16A13-associated genes across cancer lineages are WNT2, SLC17A3, and SIT1. Each is linked with SLC16A13 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC16A13-to-partner and partner-to-SLC16A13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, WNT2 grouped by SLC16A13-low versus SLC16A13-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A13→partner) and Y-score (partner→SLC16A13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINWNT2 →+0.657+3.426.002.00731
SKINSLC17A3 →+0.081+3.817.002.00231
SKINSIT1 →+0.096+3.426<.001.00731
SKINOR11H4 →+0.027+3.321.007.00531
SKINOR56A3 →+0.180+2.994<.001.00631
SKINSHOX →+0.036+3.760<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

WNT2 by SLC16A13 expression — SKIN

Box plot of WNT2 in SLC16A13-low vs SLC16A13-high samples in SKIN.

Explore this box plot interactively →

Exploration