SLC16A12

Across TCGA patient cohorts, SLC16A12 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC16A12-associated genes across cancer lineages are Cyclin-B1, Caspase-8, and Cyclin-E2. Each is linked with SLC16A12 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC16A12-to-partner and partner-to-SLC16A12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cyclin-B1 grouped by SLC16A12-low versus SLC16A12-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A12→partner) and Y-score (partner→SLC16A12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-B1 →	+0.486	+3.169	.021	.018	3	3
UCEC	Caspase-8 →	-0.205	-2.558	.029	.010	3	2
UCEC	Cyclin-E2 →	+0.143	+1.415	.024	.046	3	2
UCEC	14-3-3_beta →	-0.078	-1.752	.039	.014	3	1
UCEC	EGFR_pY1068 →	-0.232	-2.169	.013	.003	3	1
UCEC	ERK2 →	+0.209	+1.765	.003	.014	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

Cyclin-B1 by SLC16A12 expression — UCEC

Explore this box plot interactively →