SLC16A12

Across TCGA cell cohorts, SLC16A12 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,925 significant associations in total. CNS shows the largest number of these associations.

The most reproducible SLC16A12-associated GO terms across cancer lineages are Regulation of actin filament organization, Positive regulation of intracellular transport, and Positive regulation of cell-substrate adhesion. Each is linked with SLC16A12 in more than 8 cancer types. Because this analysis shows association rather than direction, both SLC16A12-to-partner and partner-to-SLC16A12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of actin filament organization grouped by SLC16A12-low versus SLC16A12-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A12→partner) and Y-score (partner→SLC16A12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of actin filament organization →	+0.045	+0.950	.004	.005	3	9
BONE	Positive regulation of intracellular transport →	+0.058	+0.279	<.001	.004	3	9
KIDNEY	Positive regulation of cell-substrate adhesion →	+0.098	+1.548	.001	.001	3	8
BONE	Integrin-mediated signaling pathway →	+0.165	+0.276	.002	.005	3	8
LUNG_NSCLC_LUSC	Protein lipidation →	+0.093	+0.348	.004	.006	2	9
LUNG_NSCLC_LUSC	Regulation of actin filament bundle assembly →	+0.066	+0.349	.001	.005	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,925 associations by consensus.

Regulation of actin filament organization by SLC16A12 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →