SLC16A11

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC16A11 mutation is significantly associated with the RNA expression of many other genes, with 76 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC16A11-associated genes across cancer lineages are MIR7702, MIR1273H, and MIR6793. Each is linked with SLC16A11 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC16A11-to-partner and partner-to-SLC16A11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR7702 grouped by SLC16A11-low versus SLC16A11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A11→partner) and Y-score (partner→SLC16A11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR7702 →+0.373+5.060<.001.00131
UCECMIR1273H →+0.255+3.399<.001.00531
UCECMIR6793 →+0.735+2.749.003.00331
COADRNU6-1250P →+0.378+4.693.001.00731
SKCMLINC02149 →+0.049+4.970<.001.00531
CESCLINC00440 →+0.081+7.164<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 76 associations by consensus.

MIR7702 by SLC16A11 expression — UCEC

Box plot of MIR7702 in SLC16A11-low vs SLC16A11-high samples in UCEC.

Explore this box plot interactively →

Exploration