SLC16A11

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC16A11 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC16A11-associated genes across cancer lineages are TAFA1, IQCF6, and ASB17. Each is linked with SLC16A11 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC16A11-to-partner and partner-to-SLC16A11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAFA1 grouped by SLC16A11-low versus SLC16A11-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A11→partner) and Y-score (partner→SLC16A11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINETAFA1 →+0.402+4.273<.001.00631
LARGE_INTESTINEIQCF6 →+0.311+4.467<.001.00431
OVARYASB17 →+0.023+5.807<.001.00131
OVARYRBMY1A1 →+0.143+5.807<.001.00131
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

TAFA1 by SLC16A11 expression — LARGE_INTESTINE

Box plot of TAFA1 in SLC16A11-low vs SLC16A11-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration