SLC16A10

Across TCGA patient cohorts, SLC16A10 mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC16A10-associated genes across cancer lineages are MSH6, ACC_pS79, and MEK1. Each is linked with SLC16A10 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC16A10-to-partner and partner-to-SLC16A10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MSH6 grouped by SLC16A10-low versus SLC16A10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A10→partner) and Y-score (partner→SLC16A10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MSH6 →	-0.360	-1.678	.004	.023	3	2
UCEC	ACC_pS79 →	+0.286	+2.331	.031	.019	3	1
UCEC	MEK1 →	+0.281	+2.321	.045	.033	3	1
UCEC	p62 Lck ligand →	+0.259	+2.594	.038	.006	3	1
UCEC	Annexin-1 →	+0.539	+3.341	.007	.005	3	1
UCEC	TIGAR →	+0.182	+1.704	.001	.013	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

MSH6 by SLC16A10 expression — UCEC

Explore this box plot interactively →